Merged widgets.js does not work on premise

I upgraded from 5.10 to 5.16.1. The server is on promise. The widgets.js fails to load in IIS (3-tier setup). If I replace it with the simple local widgets.js (only require(...) it works. Do I need to setup something to get it to work in IIS? It contains specific commands for caching. The console gives no error messages.
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