Hi Venkatesh ,
You can integrate the Sharepoint in to Mendix application with the help of Rest API .
Please refer the existing blogs on Sharepoint Integration using Rest API
Sharepoint API : https://learn.microsoft.com/en-us/graph/api/overview?view=graph-rest-1.0
https://www.indiumsoftware.com/blog/read-excel-data-from-sharepoint-using-graph-api/
https://medium.com/mendix/upload-a-file-to-sharepoint-using-mendix-5f8f6c696a42