Hi Deepak,
this heavily depends on the meaning of your data. If all 1450 columns are necessary everytime you get a respective object, then the answer is “No”. But if there is only a partial set of columns needed, and the rest can be fetched when needed, then you should split it up.
Best have a look at https://docs.mendix.com/howto/general/community-best-practices-for-app-performance
Here are some do’s and don’t summarized, which should help you with your decision