Random lag spikes sitewide

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On our mendix site, we’re having seemingly random spikes of connections and slowness. In the error logs we get this:   3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPERRORConnectionBus: Opening JDBC connection to Some(dbxwyhkxunf7dpc5n.cxo3eatbis4c.us-east-1.rds.amazonaws.com:5432) failed with SQLState: 53300 Error code: 0 Message: FATAL: sorry, too many clients already Retrying...(1/4) 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPERRORConnectionBus: Opening JDBC connection to Some(dbxwyhkxunf7dpc5n.cxo3eatbis4c.us-east-1.rds.amazonaws.com:5432) failed with SQLState: 53300 Error code: 0 Message: FATAL: sorry, too many clients already Retrying...(1/4) 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPERRORConnectionBus: Opening JDBC connection to Some(dbxwyhkxunf7dpc5n.cxo3eatbis4c.us-east-1.rds.amazonaws.com:5432) failed with SQLState: 53300 Error code: 0 Message: FATAL: sorry, too many clients already Retrying...(1/4) 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPERRORConnectionBus: Opening JDBC connection to Some(dbxwyhkxunf7dpc5n.cxo3eatbis4c.us-east-1.rds.amazonaws.com:5432) failed with SQLState: 53300 Error code: 0 Message: FATAL: sorry, too many clients already Retrying...(1/4) 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPERRORConnectionBus: Opening JDBC connection to Some(dbxwyhkxunf7dpc5n.cxo3eatbis4c.us-east-1.rds.amazonaws.com:5432) failed with SQLState: 53300 Error code: 0 Message: FATAL: sorry, too many clients already Retrying...(1/4) 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle. 3:39:42 PMAPPWARNINGConnectionBus: Database connections: 26 active, 9 idle.   Has anyone seen this before?
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